Reviewed by Dr. Gretchen San Miguel, MD. Triple Board Certified in Family Medicine, Geriatrics, and Obesity Medicine. Founder, Vivant Medical Concierge.
How do amino acids support skin?
The short answer: Amino acids are the building blocks your body uses to support the proteins tied to skin structure, including collagen. Supplying these building blocks directly gives the body usable raw material, which is a different approach from ingesting finished collagen peptides. In a skin formula, amino acids add a structural support dimension that hydration ingredients alone do not.

Building blocks versus finished proteins
When you ingest a finished protein like collagen, your body breaks it down into smaller pieces during digestion before it can use them. Providing the amino acid building blocks directly skips ahead to what the body actually works with. The three most associated with collagen structure are glycine, proline, and lysine. The research on these is detailed on our clinical research page.
This distinction is the reason building-block formulas and peptide formulas are not the same thing, even when both are marketed for skin. One supplies a finished protein the body has to disassemble; the other supplies the components directly.
How H2Glow uses amino acids
H2Glow's HydraCollagen Matrix supplies glycine, proline, and lysine at 500mg each, 1,500mg in total, as the structural support part of its system. Because these aminos are not animal-derived, the approach also keeps the formula vegan, unlike collagen peptides.
The matrix is one part of a broader system of 17 actives that also covers hydration and moisture retention, rather than a single ingredient working alone. The fuller picture is in our pillar on collagen for skin hydration, the amino acid detail is on our research page, and you can compare this approach to a peptide product on our H2Glow vs. Vital Proteins comparison.

Frequently asked questions
How do amino acids support skin structure?
Amino acids are building blocks involved in supporting proteins tied to skin structure. In beauty hydration formulas, they complement hydration ingredients by adding a structural support angle.
Are amino acids better than collagen for skin?
They are a different approach. Amino acids are the building blocks the body uses, while collagen is a finished protein the body breaks down during digestion. Supplying building blocks directly is one rationale for using aminos.
Which amino acids matter for skin?
Glycine, proline, and lysine are the three most associated with collagen structure, which is why they appear together in skin-focused formulas.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. These statements are based on clinical research on individual ingredients. Results may vary.